# Risks of Losing Sleep Short-term physiological risks (within 1-2 days of lost sleep): - Slowed metabolism and increased appetite - Increased inflammation - Slowed healing and a weakened immune system - Vaccines are less effective - High blood pressure - Irregular heartbeats - Physically weaker - Chronic pain intensified - Diminished reaction time - Exponentially higher risk of auto accidents - Disrupted circadian rhythm (your natural clock) - Tremors and shakes - Aches - Reduced accuracy at all tasks - Lower body temperature - Slurred speech Chronic physiological risks (can persist for weeks afterward): - Increased risk of cancer, diabetes, heart disease, stroke, and Alzheimer’s disease - Weight gain - Permanent skin damage - Diminished life expectancy - Damaged bone tissue - Stunted growth - Damaged brain tissue - General increased chance of dying Psychological risks: - Higher chance of depression - Unstable mood swings and distress - Increased anxiety and irritability - Difficulty reading others’ emotions - Cluttered thoughts - Delusions and hallucinations - Impeded learning - Less ability to manage stress - Impaired judgment - Inhibited [creativity](mind-creativity.md) - Problems with retaining, storing or retrieving information - Increased perception of pain - Behavior and thinking that closely resemble getting a concussion - Increased chance of [substance abuse](addiction-substances.md), specifically alcohol and caffeine